In order to truly re-see your draft from the point of view of your reader, it is very useful to put it aside for a while before rereading it, preferably for at least a day.
If you can, try to plan to have your draft finished so that you will have enough time to take a break between drafts. If you don't have a day, try to take some time away from your work completely (take a walk, play some video games, go to the mall, whatever) to clear your head. Taking a break can help you:
You may wish to review the Time Management module to learn about scheduling your time more effectively.